Creating a test to detect HIV and Hepatitis B in low-income countries
Development of a Multiplex Quantitative PCR Assay for HIV and Hepatitis B Virus, for Low- and middle Income Countries
This study is testing a new blood test that can quickly find both HIV and Hepatitis B infections, especially for people in places like Mali, so doctors can provide better treatment for those at risk.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Univ of Sciences, Tech & Tech of Bamako NIH-funded |
| Lab location | 1 site (Bamako, Mali) |
| Project ID | NIH-11093357 on NIH RePORTER |
What this research studies
This research focuses on developing a multiplex quantitative PCR assay to detect both HIV and Hepatitis B virus (HBV) infections, particularly in low- and middle-income countries like Mali. The approach aims to improve early detection of HBV, which often goes unnoticed due to its asymptomatic nature, especially in individuals already at risk for HIV. By accurately identifying these infections, healthcare providers can better tailor antiretroviral therapy regimens to improve patient outcomes. The study will involve collecting and analyzing blood samples to validate the effectiveness of the new testing method.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals living in Mali who are at risk for HIV and Hepatitis B, particularly those in high-prevalence groups such as pregnant women and blood donors.
Not a fit: Patients who are not at risk for HIV or Hepatitis B, or those living outside of the targeted geographic area, may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved early detection and treatment of HIV and Hepatitis B, ultimately reducing complications and mortality rates in affected populations.
How similar studies have performed: Previous research has shown success in developing similar assays for viral detection, indicating a promising potential for this approach in low-resource settings.
Where this research is happening
Bamako, Mali
- Univ of Sciences, Tech & Tech of Bamako — Bamako, Mali (Active)
Researchers
- Principal investigator: Fofana, Djeneba Bocar — Univ of Sciences, Tech & Tech of Bamako
- Study coordinator: Fofana, Djeneba Bocar
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.