Creating a technology to verify engineered DNA molecules

Supplement: Development of a technology to certify engineered DNA molecules

['FUNDING_R01'] · COLORADO STATE UNIVERSITY · NIH-11093797

This study is working on a new digital system to make sure that the engineered DNA used in treatments like gene therapy and vaccines is safe and properly documented, which could lead to better and safer treatments for patients.

Quick facts

Phase['FUNDING_R01']
Study typeNih_funding
SexAll
SponsorCOLORADO STATE UNIVERSITY (nih funded)
Locations1 site (FORT COLLINS, UNITED STATES)
Trial IDNIH-11093797 on ClinicalTrials.gov

What this research studies

This research focuses on developing a digital certification technology to ensure the authenticity and proper documentation of engineered DNA molecules, particularly plasmids. By addressing issues such as labeling errors and undocumented modifications, the project aims to create a secure and standardized method for tracking the lineage and function of plasmids used in clinical applications like gene therapy and vaccine development. Patients may benefit from improved safety and efficacy in treatments that rely on these engineered DNA molecules.

Who could benefit from this research

Good fit: Ideal candidates for participation or benefit from this research include individuals involved in clinical trials for gene therapies or vaccines that utilize engineered DNA.

Not a fit: Patients who are not undergoing gene therapy or vaccine treatments may not receive direct benefits from this research.

Why it matters

Potential benefit: If successful, this research could enhance the safety and reliability of gene therapies and vaccines for patients.

How similar studies have performed: While the approach of certifying engineered DNA molecules is innovative, similar methodologies in ensuring the authenticity of biological materials have shown promise in other areas of biomedical research.

Where this research is happening

FORT COLLINS, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.