Creating a system to track and improve HIV prevention efforts using PrEP data
Official title: Establishing PREMISE: A PrEP Epidemiology, Modeling, and Surveillance System
Funded at Emory University · NIH-11009421 · Data updated 2026-11-12
This study is looking at how well people are using a medication called PrEP to prevent HIV, especially in communities that might not have easy access to it, so we can find better ways to help everyone stay healthy.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Emory University NIH-funded |
| Lab location | 1 site (Atlanta, United States) |
| Project start | August 14, 2024 |
| Project end | June 30, 2029 |
| Funding year | 2024 |
| Award (this year) | $911,400 |
| NIH project number | 1R01AI181799-01A1 |
| Project ID | NIH-11009421 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include individuals at high risk for HIV who may benefit from PrEP, particularly within Black communities.
✕Less likely to help
Patients who are not at risk for HIV or those who are already receiving effective HIV prevention measures may not benefit from this research.
What this research studies
This research aims to establish a comprehensive system called PREMISE that will collect and analyze national data on the use of pre-exposure prophylaxis (PrEP) for HIV prevention. By examining patterns of PrEP uptake and the effectiveness of various programs and policies, the research seeks to identify strategies that enhance access to and use of PrEP, particularly among underserved populations. The team will utilize diverse datasets and legal coding to understand the impact of different local policies on PrEP utilization. This approach will help inform public health responses to the HIV epidemic and improve prevention efforts across the United States.
Why it matters
Potential benefit: If successful, this research could lead to improved access to HIV prevention methods for at-risk populations, ultimately reducing the incidence of HIV.
How similar studies have gone: Previous research has shown that targeted programs and policies can significantly increase PrEP uptake, indicating that this approach has potential for success.
Where this research is happening
-
Emory University
Atlanta, United States Active
Researchers
- Principal investigator: Siegler, Aaron Julius — Emory University
- Study coordinator: Siegler, Aaron Julius
Related research
Other NIH-funded projects on the same topics.
-
mChoice: Boosting PrEP Use and Adherence for Black and Latino MSM with Tailored Training and Support
A national study to help Black and Latino men who have sex with men start and stick with PrEP through culturally matched provider training and patient support.
-
Harnessing male peer networks to boost HIV testing and PrEP use
A large clinical trial in South Africa tests whether giving HIV self-test kits through male peer networks, with phone support, increases PrEP uptake among men.
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Harnessing men's peer networks to boost HIV self-testing and PrEP use
A large project in South Africa tests whether giving HIV self-test kits through men’s social networks, with phone support, can lead to more men starting PrEP and using HIV testing.
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Participatory system dynamics to improve PrEP access in the Bronx
A community-driven project in the Bronx will use system dynamics to identify practical ways to help people at risk for HIV start and stay on PrEP.
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TB PrEP: Bringing HIV prevention to households affected by TB in Uganda
Aims to help people in households with TB in Uganda access HIV PrEP as part of a combined prevention approach.
-
CARES: A practical program to help adolescent girls and young women use PrEP in Africa
A program called CARES helps young women in South Africa and Zimbabwe use different PrEP options better, with counseling, reminders, and options for support.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.