Creating a system to cool injured brain tissue using advanced technology
Development of AI/ML-ready shared repository for parametric multiphysics modeling datasets: standardization for predictive modeling of selective brain cooling after traumatic injury
This study is working on a new device that cools down injured brain tissue quickly to help people recover better from head injuries, and it will use data to improve how the device works and how doctors plan treatments.
Quick facts
| Grant type | R21 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Duke University NIH-funded |
| Lab location | 1 site (Durham, United States) |
| Project ID | NIH-10842926 on NIH RePORTER |
What this research studies
This research focuses on developing a device that can rapidly cool injured brain tissue to reduce the long-term effects of head trauma. The device will be inserted into existing catheters used for monitoring intracranial pressure. Additionally, the project aims to create a standardized repository of data that can be used with artificial intelligence and machine learning to optimize the device's design and treatment planning. By making complex simulation data accessible for AI/ML applications, the research seeks to enhance predictive modeling capabilities in clinical settings.
Who could benefit from this research
Good fit: Ideal candidates for this research are patients who have experienced traumatic brain injuries and require intracranial pressure monitoring.
Not a fit: Patients with non-traumatic brain conditions or those who do not require intracranial pressure management may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved treatment options for patients with traumatic brain injuries, potentially reducing long-term complications.
How similar studies have performed: Other research has shown promise in using AI/ML for biomedical applications, but this specific approach to cooling brain tissue is novel.
Where this research is happening
Durham, United States
- Duke University — Durham, United States (Active)
Researchers
- Principal investigator: Maccarini, Paolo Francesco — Duke University
- Study coordinator: Maccarini, Paolo Francesco
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.