Creating a system to connect genomic data with patient care information
Instrumenting the Delivery System for a Genomics Research Information Commons
This study is working to connect genetic information with health records from children's hospitals to see how different genes can affect treatment and recovery, helping doctors provide more personalized care for kids.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Boston Children's Hospital NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project ID | NIH-10884147 on NIH RePORTER |
What this research studies
This research aims to develop a comprehensive system that links genetic information with clinical data to better understand how genetic variants affect patient outcomes. By utilizing a federated biobanking initiative across multiple children's hospitals, the project will create a Genomics Information Commons that allows researchers to access a diverse dataset of patient information. This will help in assessing the pathogenicity of genetic variants and their impact on treatment and prognosis, ultimately improving personalized medicine approaches for patients. The initiative will also address the challenges of varying IT systems and regulatory requirements across institutions.
Who could benefit from this research
Good fit: Ideal candidates for this research include pediatric patients with genetic variants or those at risk for genetic disorders.
Not a fit: Patients without genetic variants or those not seeking personalized treatment approaches may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more accurate diagnoses and tailored treatment plans based on individual genetic profiles.
How similar studies have performed: Other research initiatives have successfully linked genomic data with clinical outcomes, suggesting that this approach has the potential for significant advancements in personalized medicine.
Where this research is happening
Boston, United States
- Boston Children's Hospital — Boston, United States (Active)
Researchers
- Principal investigator: Mandl, Kenneth D. — Boston Children's Hospital
- Study coordinator: Mandl, Kenneth D.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.