Creating a specialized patch to heal heart tissue damage
Engineered Anisotropic and Vascularized Human Cardiac Patch
['FUNDING_R01'] · TEXAS ENGINEERING EXPERIMENT STATION · NIH-10652538
This study is testing a special heart patch made from human cells that could help heal heart tissue damaged by a heart attack, making it easier for your heart to recover and grow new blood vessels.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | TEXAS ENGINEERING EXPERIMENT STATION (nih funded) |
| Locations | 1 site (COLLEGE STATION, UNITED STATES) |
| Trial ID | NIH-10652538 on ClinicalTrials.gov |
What this research studies
This research focuses on developing an engineered cardiac patch that aims to regenerate heart tissue damaged by myocardial infarction. The approach involves using human pluripotent stem cell-derived cardiac fibroblasts to create a scaffold that mimics natural heart tissue, promoting better integration and healing. The patch will also incorporate human mesenchymal stem cells to enhance blood vessel formation and support tissue regeneration. By combining these elements, the project seeks to improve the effectiveness of heart tissue repair.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals who have experienced a myocardial infarction and have ongoing heart tissue damage.
Not a fit: Patients with non-cardiac related health issues or those who have not experienced heart damage may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could provide a new therapeutic option for patients suffering from heart damage, potentially improving recovery and heart function.
How similar studies have performed: Previous research in tissue engineering has shown promise in developing similar cardiac patches, indicating potential for success in this novel approach.
Where this research is happening
COLLEGE STATION, UNITED STATES
- TEXAS ENGINEERING EXPERIMENT STATION — COLLEGE STATION, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: ZHAO, FENG — TEXAS ENGINEERING EXPERIMENT STATION
- Study coordinator: ZHAO, FENG
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.