Creating a skin patch to relieve nausea and vomiting during pregnancy

Who could benefit from this research

What this research studies

This research focuses on developing a transdermal patch that delivers ondansetron, a medication used to treat pregnancy-induced nausea and vomiting (PINV). The patch is designed to be applied once or twice a week, providing a continuous release of the medication without the need for oral ingestion, which can be difficult for those experiencing severe nausea. The project aims to enhance the absorption of ondansetron through the skin significantly, making it a more effective treatment option for pregnant individuals suffering from PINV. The research has already received guidance from the FDA on the regulatory approval process, indicating a clear path forward for the product's development.

Why it matters

Where this research is happening

• Integurx Therapeutics LLC
  Califon, United States Active

Researchers

• Principal investigator: Shangold, Gary — Integurx Therapeutics LLC
• Study coordinator: Shangold, Gary

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About this research

1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.