Creating a simulator to improve brain-machine interfaces for movement disorders

An Open Source Simulator for Multi Degree-Of-Freedom Brain-Machine Interfaces

['FUNDING_R01'] · UNIVERSITY OF CALIFORNIA LOS ANGELES · NIH-11092766

This study is creating a helpful computer program that simulates brain activity to make it easier and faster for researchers to improve devices that assist people with movement disorders like paralysis and ALS, aiming to enhance their ability to use prosthetics and communicate.

Quick facts

Phase['FUNDING_R01']
Study typeNih_funding
SexAll
SponsorUNIVERSITY OF CALIFORNIA LOS ANGELES (nih funded)
Locations1 site (LOS ANGELES, UNITED STATES)
Trial IDNIH-11092766 on ClinicalTrials.gov

What this research studies

This research focuses on developing an open-source simulator designed to enhance brain-machine interfaces (BMIs) for individuals with movement disorders such as paralysis and ALS. By utilizing neural encoding models, the simulator will generate synthetic brain activity to evaluate and optimize BMI algorithms quickly and efficiently. This approach aims to reduce the time required for testing from months to mere minutes, thereby broadening the pool of researchers who can contribute to the development of these technologies. Ultimately, the goal is to improve the functionality of prosthetic devices that can restore motor function and communication for patients.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals suffering from movement disorders, including those with paralysis or ALS, who may benefit from advanced brain-machine interface technologies.

Not a fit: Patients with movement disorders who are not candidates for brain-machine interfaces or those who do not have access to the necessary technology may not receive benefits from this research.

Why it matters

Potential benefit: If successful, this research could lead to faster and more effective development of brain-machine interfaces, significantly improving the quality of life for patients with movement disorders.

How similar studies have performed: Other research has shown promise in developing brain-machine interfaces, but this simulator represents a novel approach aimed at accelerating algorithm development.

Where this research is happening

LOS ANGELES, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.