Creating a safer system to study hantavirus entry proteins
Development of a novel BSL2 system for high-throughput analysis of hantavirus entry glycoproteins
This study is working on a new way to safely study the proteins that help hantaviruses enter human cells, which could lead to better treatments and vaccines for serious diseases caused by these viruses, ultimately helping patients like you.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Louisiana State Univ Hsc Shreveport NIH-funded |
| Lab location | 1 site (Shreveport, United States) |
| Project ID | NIH-11041019 on NIH RePORTER |
What this research studies
This research focuses on developing a new biosafety level 2 (BSL2) system to analyze the entry glycoproteins of hantaviruses, which are responsible for serious diseases like hantavirus cardiopulmonary syndrome and hemorrhagic fever with renal syndrome. By improving the ability to study these proteins, the research aims to enhance our understanding of how hantaviruses infect human cells and elicit immune responses. The approach involves creating a scalable system that allows for comprehensive genetic analysis of the glycoproteins, which could lead to better insights into potential vaccines and therapies. Patients may benefit from advancements in treatment options as a result of this research.
Who could benefit from this research
Good fit: Ideal candidates for participation or benefit from this research would include individuals at risk of hantavirus infections, particularly those in endemic areas.
Not a fit: Patients who are not at risk for hantavirus infections or those with existing effective treatments may not receive benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to the development of effective vaccines or therapies for hantavirus infections.
How similar studies have performed: While there have been advancements in studying other viral entry mechanisms, this specific approach to hantavirus research is relatively novel and untested.
Where this research is happening
Shreveport, United States
- Louisiana State Univ Hsc Shreveport — Shreveport, United States (Active)
Researchers
- Principal investigator: Jangra, Rohit K — Louisiana State Univ Hsc Shreveport
- Study coordinator: Jangra, Rohit K
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.