Creating a resource platform for curative therapies for sickle cell disease.
CureSC Manufacturing Resource Platform
This study is working to create a helpful resource for making new treatments for sickle cell disease by figuring out what the sickle cell community needs and teaming up with experts to improve how these therapies are produced.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Beckman Research Institute/city of Hope NIH-funded |
| Lab location | 1 site (Duarte, United States) |
| Project ID | NIH-10908840 on NIH RePORTER |
What this research studies
This research aims to establish a comprehensive manufacturing resource platform to support the development of curative genetic therapies for sickle cell disease (SCD). The City of Hope team will conduct a needs assessment to understand the specific requirements of the sickle cell community regarding cell and vector product manufacturing. They will evaluate current manufacturing capabilities and collaborate with experts to create a strategic plan for a consortium that addresses these needs. This initiative will ultimately facilitate the production of essential therapies for patients with SCD.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with sickle cell disease who may benefit from advanced genetic therapies.
Not a fit: Patients with other blood disorders or those not affected by sickle cell disease may not receive any benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved access to effective curative therapies for patients with sickle cell disease.
How similar studies have performed: Previous research has shown promise in developing gene therapies for blood disorders, indicating that this approach could be effective.
Where this research is happening
Duarte, United States
- Beckman Research Institute/city of Hope — Duarte, United States (Active)
Researchers
- Principal investigator: Cardoso, Angelo a. — Beckman Research Institute/city of Hope
- Study coordinator: Cardoso, Angelo a.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.