Creating a resource of non-human primate models for human genetic diseases
Official title: A National NHP Embryo Resource of Human Genetic Disease Models
Funded at Oregon Health & Science University · NIH-11003343 · Data updated 2026-11-12
This study is working to create a special resource of non-human primates that can help scientists test new treatments for genetic diseases that affect humans, with the hope of finding better options for patients facing tough health challenges.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Oregon Health & Science University NIH-funded |
| Lab location | 1 site (Portland, United States) |
| Project start | March 1, 2023 |
| Project end | December 31, 2026 |
| Funding year | 2025 |
| Award (this year) | $494,142 |
| NIH project number | 5R24OD034055-03 |
| Project ID | NIH-11003343 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for participation or benefit from this research are individuals with genetic diseases that have been modeled in non-human primates.
✕Less likely to help
Patients with common conditions that do not have a genetic basis may not receive any benefit from this research.
What this research studies
This research aims to establish a national resource for preserving and utilizing non-human primate (NHP) models that mimic human genetic diseases. By developing these models, the project seeks to facilitate the testing of new therapies and precision medicine approaches that could lead to breakthroughs in treating currently uncurable conditions. The research will focus on overcoming challenges related to breeding and availability of these models, ensuring that they can be effectively used in pre-clinical testing. Patients may benefit from advancements in treatment options that arise from this innovative approach.
Why it matters
Potential benefit: If successful, this research could lead to the development of new therapies for genetic diseases that currently have no cure.
How similar studies have gone: Other research has shown success in using animal models for studying human diseases, making this approach promising and not entirely novel.
Where this research is happening
-
Oregon Health & Science University
Portland, United States Active
Researchers
- Principal investigator: Sherman, Larry S. — Oregon Health & Science University
- Study coordinator: Sherman, Larry S.
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.