Creating a resource of mouse models to study peroxisomes
A Mouse Model Resource for Peroxisome Research
['FUNDING_OTHER'] · UNIVERSITY OF SOUTHERN CALIFORNIA · NIH-11012278
This study is creating helpful tools for scientists to learn more about peroxisomes, which are important for keeping our cells and organs working well, so they can better understand disorders related to these tiny structures and how they affect our health.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF SOUTHERN CALIFORNIA (nih funded) |
| Locations | 1 site (Los Angeles, UNITED STATES) |
| Trial ID | NIH-11012278 on ClinicalTrials.gov |
What this research studies
This research focuses on developing a comprehensive resource of mouse models and monoclonal antibodies to better understand peroxisomes, which are crucial for cell signaling and the normal functioning of human organ systems. By addressing the limitations of existing models, the project aims to provide researchers with accessible tools to investigate peroxisome-related disorders and their underlying genetic factors. The approach includes creating well-annotated models that can be used for both basic and translational research, ultimately enhancing our understanding of peroxisome biology and its implications for human health.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with rare monogenic disorders linked to peroxisome dysfunction or those who may benefit from advancements in understanding these conditions.
Not a fit: Patients with conditions unrelated to peroxisome dysfunction or those not affected by genetic disorders may not receive any benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding and treatment options for rare genetic disorders associated with peroxisome dysfunction.
How similar studies have performed: Previous research has shown success in developing mouse models for other genetic disorders, suggesting that this approach could yield valuable insights into peroxisome-related conditions.
Where this research is happening
Los Angeles, UNITED STATES
- UNIVERSITY OF SOUTHERN CALIFORNIA — Los Angeles, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: HACIA, JOSEPH G — UNIVERSITY OF SOUTHERN CALIFORNIA
- Study coordinator: HACIA, JOSEPH G
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.