Creating a realistic 3D model of the human cornea for keratoconus treatment

Advanced 3D model of the Human Cornea for Keratoconus

['FUNDING_SBIR_1'] · CFD RESEARCH CORPORATION · NIH-10821906

This study is creating a detailed 3D model of the eye's cornea to help us understand keratoconus better, which could lead to better treatments and tools for people dealing with this vision loss condition.

Quick facts

Phase['FUNDING_SBIR_1']
Study typeNih_funding
SexAll
SponsorCFD RESEARCH CORPORATION (nih funded)
Locations1 site (HUNTSVILLE, UNITED STATES)
Trial IDNIH-10821906 on ClinicalTrials.gov

What this research studies

This research focuses on developing an advanced 3D model of the human cornea to better understand keratoconus, a condition that leads to progressive vision loss. The project aims to create a model that accurately reflects the corneal curvature and incorporates the flow of tear film and aqueous humor, which are crucial for studying the disease and potential treatments. By addressing the limitations of existing corneal models, this research seeks to provide a more physiologically relevant platform for testing therapies and understanding the disease's progression. Patients may benefit from improved treatment options and better diagnostic tools as a result of this work.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals diagnosed with keratoconus or those experiencing progressive vision loss related to corneal degradation.

Not a fit: Patients with corneal conditions unrelated to keratoconus may not receive benefits from this research.

Why it matters

Potential benefit: If successful, this research could lead to more effective treatments and diagnostic methods for patients with keratoconus.

How similar studies have performed: While there have been advancements in corneal modeling, this approach is novel and aims to fill significant gaps in current research.

Where this research is happening

HUNTSVILLE, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Conditions: Corneal Disorder, cornea disorder

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.