Creating a quick test for congenital cytomegalovirus infection using dried blood samples
Development of a High Throughput Assay for Rapid Screening of Congenital Cytomegalovirus Infection using Dried Blood Spots
This study is working on a quick and cost-effective test to check for congenital cytomegalovirus (cCMV) in newborns using a small blood sample taken at birth, so that babies who need treatment can get it right away to help their language development.
Quick facts
| Grant type | Sbir 2 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Microgen, LLC NIH-funded |
| Lab location | 1 site (La Marque, United States) |
| Project ID | NIH-10878871 on NIH RePORTER |
What this research studies
This research focuses on developing a fast and affordable test to diagnose congenital cytomegalovirus (cCMV) infection in newborns using dried blood spots collected at birth. The innovative One-Step platform aims to provide results within 30 minutes, which is crucial for timely antiviral treatment that can improve language development in affected children. By enhancing the sensitivity of detection compared to current methods, this project seeks to facilitate early diagnosis and intervention, particularly for asymptomatic infants who may later experience hearing loss.
Who could benefit from this research
Good fit: Ideal candidates for this research are newborns and infants up to 4 weeks old who are at risk for congenital cytomegalovirus infection.
Not a fit: Patients who are older than 4 weeks or those who do not have dried blood spots available for testing may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to earlier diagnosis and treatment of cCMV infection, significantly improving language development outcomes for affected children.
How similar studies have performed: Previous research has shown that rapid diagnostic tests for infectious diseases can significantly improve treatment outcomes, suggesting a promising potential for this novel approach.
Where this research is happening
La Marque, United States
- Microgen, LLC — La Marque, United States (Active)
Researchers
- Principal investigator: Stowe, Raymond Preston — Microgen, LLC
- Study coordinator: Stowe, Raymond Preston
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.