Creating a quick blood test for colorectal cancer detection in low-income countries
Development of an automated, point of care DNA methylation cartridge blood test for colorectal cancer detection in LMICs- an academic-industrial partnership
This study is working on a quick and easy blood test to help find colorectal cancer early, especially for people in low- and middle-income countries who might not have easy access to other tests, so they can get the care they need sooner.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Johns Hopkins University NIH-funded |
| Lab location | 1 site (Baltimore, United States) |
| Project ID | NIH-11078739 on NIH RePORTER |
What this research studies
This research aims to develop an automated blood test that can quickly detect colorectal cancer (CRC) using a small sample of plasma. By focusing on low- and middle-income countries, the project addresses the significant delays in CRC diagnosis due to limited access to colonoscopy and a lack of awareness about cancer symptoms. The test will analyze specific genetic markers associated with CRC, allowing for faster identification of patients who need further examination. The goal is to create a cost-effective solution that can be deployed in community health settings, improving early detection and treatment outcomes.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals in low- and middle-income countries who are at risk for colorectal cancer, particularly those with limited access to diagnostic facilities.
Not a fit: Patients in high-income countries with established screening programs may not benefit directly from this research.
Why it matters
Potential benefit: If successful, this research could significantly reduce the mortality rate from colorectal cancer in low- and middle-income countries by enabling earlier diagnosis.
How similar studies have performed: Previous research has shown promise in using blood tests for cancer detection, indicating that this approach could be effective, though this specific application is innovative.
Where this research is happening
Baltimore, United States
- Johns Hopkins University — Baltimore, United States (Active)
Researchers
- Principal investigator: Sukumar, Saraswati — Johns Hopkins University
- Study coordinator: Sukumar, Saraswati
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.