Creating a quick and easy test to detect low levels of SARS-CoV-2 in saliva.
Developing a Rapid, Simple-to-use Sensory Platform for Detection of Ultralow Concentration of SARS-CoV-2 Viral Particles Enabled by Electrophoretic Enhancement and Redox Cycling
This study is working on a new, easy-to-use test that can quickly and accurately detect the COVID-19 virus in saliva, giving results in under 30 minutes without complicated steps, making it perfect for use right where you need it.
Quick facts
| Grant type | R21 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Pennsylvania State University, the NIH-funded |
| Lab location | 1 site (University Park, United States) |
| Project ID | NIH-10195022 on NIH RePORTER |
What this research studies
This research aims to develop a novel electrochemical sensing platform that can rapidly and accurately detect SARS-CoV-2 viral particles in saliva. By using a combination of electrophoretic concentration and redox cycling, the platform is designed to provide results with over 90% accuracy in less than 30 minutes. This simple-to-use test eliminates the need for complex RNA extraction processes, making it suitable for point-of-care applications. The goal is to enhance the ability to diagnose COVID-19 infections quickly and effectively.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals who may be experiencing symptoms of COVID-19 or have been exposed to the virus and require rapid testing.
Not a fit: Patients who are not at risk for COVID-19 or those who have already been diagnosed and are not seeking further testing may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to faster and more accessible COVID-19 testing, improving early diagnosis and control of the virus's spread.
How similar studies have performed: Other research has shown promise in developing rapid diagnostic tests for viral infections, indicating that this approach could be effective.
Where this research is happening
University Park, United States
- Pennsylvania State University, the — University Park, United States (Active)
Researchers
- Principal investigator: Ebrahimi, Seyedehaida — Pennsylvania State University, the
- Study coordinator: Ebrahimi, Seyedehaida
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.