Creating a quick and easy blood volume test for postpartum and trauma-related bleeding
Official title: Development of a rapid, scalable, and deployable point-of-care blood volume diagnostic for monitoring postpartum and trauma-related hemorrhage
Funded at Quantiport, INC. · NIH-10603819 · Data updated 2026-11-12
This study is testing a new device that helps doctors quickly and accurately measure blood loss in patients who have just given birth or have experienced trauma, so they can provide better and faster care.
Quick facts
| Grant type | Sbir 1 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Quantiport, INC. NIH-funded |
| Lab location | 1 site (Portland, United States) |
| Project start | July 1, 2023 |
| Project end | June 30, 2025 |
| Funding year | 2023 |
| Award (this year) | $231,308 |
| NIH project number | 1R43HL167475-01 |
| Project ID | NIH-10603819 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include women who have recently given birth and are at risk of postpartum hemorrhage, as well as trauma patients experiencing significant blood loss.
✕Less likely to help
Patients who are not experiencing significant blood loss or those who are not in a postpartum state may not benefit from this research.
What this research studies
This research aims to develop a new device that can quickly and accurately measure blood volume in patients experiencing postpartum hemorrhage or trauma-related bleeding. Currently, doctors rely on subjective assessments to determine blood loss, which can lead to delays in treatment. The proposed device uses a non-imaging ultrasound transducer placed on the skin to measure the concentration of a microbubble tracer in the blood, providing a quantitative assessment of blood volume. This innovative approach seeks to enhance the speed and accuracy of diagnosing critical blood loss, ultimately improving patient care.
Why it matters
Potential benefit: If successful, this research could significantly reduce maternal mortality by enabling timely and effective treatment for postpartum hemorrhage.
How similar studies have gone: Other research has shown promise in developing point-of-care diagnostic devices for blood volume assessment, indicating that this approach could be effective.
Where this research is happening
-
Quantiport, INC.
Portland, United States Active
Researchers
- Principal investigator: Busse, Lawrence J — Quantiport, INC.
- Study coordinator: Busse, Lawrence J
Related research
Other NIH-funded projects on the same topics.
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Wearable tech to track blood loss during childbirth
A wearable device monitors cardiovascular signals to detect postpartum hemorrhage early so clinicians can act quickly to protect mothers.
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Maternal Postpartum Monitoring with a Wearable Sensor (MOMS)
A wearable system called MOMS will continuously monitor multiple physiological signals in pregnant people to detect postpartum hemorrhage earlier than standard vital signs.
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AI-powered real-time postpartum hemorrhage risk predictor in clinical care
A real-time AI tool integrated into electronic health records helps identify women at risk for postpartum hemorrhage so clinicians can intervene earlier.
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Targeting Ubiquitination to Improve Uterotonic Therapies in Postpartum Hemorrhage
A new approach aims to boost uterine contractions during childbirth and after delivery by understanding how a hormone receptor is regulated, potentially reducing postpartum hemorrhage risk.
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Personalized Postpartum Bleeding Risk Prediction with Machine Learning and Genetic Scores
This grant aims to create a personalized tool that predicts a mother’s risk of postpartum hemorrhage using machine learning and her genetic information.
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OPTIMUM OB-TXA: Timing, route, and dose of tranexamic acid to prevent postpartum bleeding before cord clamping
Aims to find the best time, method, and amount of tranexamic acid given before cord clamping to prevent postpartum hemorrhage in new mothers and protect babies.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.