Creating a quick and affordable way to detect colorectal cancer early
Development of a noninvasive, rapid and affordable method for early detection of colorectal cancer
This study is looking for a gentle and easy way to spot early signs of colorectal cancer by checking for certain cells in a simple rectal swab, which could help more people get screened and catch any issues before they become serious.
Quick facts
| Grant type | R21 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of South Carolina at Columbia NIH-funded |
| Lab location | 1 site (Columbia, United States) |
| Project ID | NIH-10456820 on NIH RePORTER |
What this research studies
This research focuses on developing a noninvasive method for early detection of colorectal cancer (CRC) that could improve screening compliance among patients. It aims to explore the concept of field effect in CRC, where subtle changes occur in the colon even before cancer develops. By analyzing cells collected through rectal swabbing, researchers hope to identify mast cells that indicate precancerous changes. This innovative approach combines advanced imaging techniques with an understanding of mast cell biology to create a new screening tool.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals at risk for colorectal cancer, particularly those who are low-income or younger patients who may not have access to traditional screening methods.
Not a fit: Patients who have already been diagnosed with colorectal cancer or those who do not have any risk factors for the disease may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to a more accessible and less invasive screening method for colorectal cancer, potentially saving lives through earlier detection.
How similar studies have performed: While the approach of using rectal swabbing for early detection is innovative, similar methods have shown promise in other areas of cancer detection, suggesting potential for success.
Where this research is happening
Columbia, United States
- University of South Carolina at Columbia — Columbia, United States (Active)
Researchers
- Principal investigator: Oskeritzian, Carole a — University of South Carolina at Columbia
- Study coordinator: Oskeritzian, Carole a
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.