Creating a public database for craniosynostosis genetic and imaging information
Official title: Human Craniosynostosis Atlas (HuCA) : Standardizing & Establishing a Public Repository for Genomic and Imaging data
Funded at Vanderbilt University Medical Center · NIH-11058170 · Data updated 2026-11-12
This study is creating a shared collection of important information about craniosynostosis, which is when a baby's skull bones fuse too soon, to help doctors better understand how it affects children's brains and development, ultimately leading to better ways to diagnose and treat the condition.
Quick facts
| Grant type | R21 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Vanderbilt University Medical Center NIH-funded |
| Lab location | 1 site (Nashville, United States) |
| Project start | September 19, 2024 |
| Project end | August 31, 2026 |
| Funding year | 2024 |
| Award (this year) | $275,405 |
| NIH project number | 1R21DE033851-01A1 |
| Project ID | NIH-11058170 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are infants and young children diagnosed with craniosynostosis.
✕Less likely to help
Patients with craniosynostosis who are older than 11 years or those without a diagnosis may not benefit from this research.
What this research studies
This research aims to establish a comprehensive public repository that collects and standardizes genomic and imaging data related to craniosynostosis, a condition where a baby's skull bones fuse too early. By gathering data from multiple sites, the project will analyze CT scans, MRI images, and genetic information to better understand the condition's effects on the brain and overall development. The goal is to improve diagnosis and treatment options for affected children by providing valuable insights to the medical community.
Why it matters
Potential benefit: If successful, this research could lead to improved diagnosis and treatment strategies for children with craniosynostosis.
How similar studies have gone: Previous research has shown success in creating similar repositories for other conditions, indicating a promising approach for craniosynostosis.
Where this research is happening
-
Vanderbilt University Medical Center
Nashville, United States Active
Researchers
- Principal investigator: Newton, Allen T — Vanderbilt University Medical Center
- Study coordinator: Newton, Allen T
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.