Creating a public database for craniosynostosis genetic and imaging information
Human Craniosynostosis Atlas (HuCA) : Standardizing & Establishing a Public Repository for Genomic and Imaging data
['FUNDING_R21'] · VANDERBILT UNIVERSITY MEDICAL CENTER · NIH-11058170
This study is creating a shared collection of important information about craniosynostosis, which is when a baby's skull bones fuse too soon, to help doctors better understand how it affects children's brains and development, ultimately leading to better ways to diagnose and treat the condition.
Quick facts
| Phase | ['FUNDING_R21'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | VANDERBILT UNIVERSITY MEDICAL CENTER (nih funded) |
| Locations | 1 site (NASHVILLE, UNITED STATES) |
| Trial ID | NIH-11058170 on ClinicalTrials.gov |
What this research studies
This research aims to establish a comprehensive public repository that collects and standardizes genomic and imaging data related to craniosynostosis, a condition where a baby's skull bones fuse too early. By gathering data from multiple sites, the project will analyze CT scans, MRI images, and genetic information to better understand the condition's effects on the brain and overall development. The goal is to improve diagnosis and treatment options for affected children by providing valuable insights to the medical community.
Who could benefit from this research
Good fit: Ideal candidates for this research are infants and young children diagnosed with craniosynostosis.
Not a fit: Patients with craniosynostosis who are older than 11 years or those without a diagnosis may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved diagnosis and treatment strategies for children with craniosynostosis.
How similar studies have performed: Previous research has shown success in creating similar repositories for other conditions, indicating a promising approach for craniosynostosis.
Where this research is happening
NASHVILLE, UNITED STATES
- VANDERBILT UNIVERSITY MEDICAL CENTER — NASHVILLE, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: NEWTON, ALLEN T — VANDERBILT UNIVERSITY MEDICAL CENTER
- Study coordinator: NEWTON, ALLEN T
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Acquired brain injury