NIH-funded research NIH-funded research

Creating a program to help people with HIV in South Africa manage mental health and social challenges.

Official title: Developing and piloting a multilevel intervention to address psychosocial and structural syndemics in people with HIV in South Africa

Funded at Massachusetts General Hospital · NIH-11237402 · Data updated 2026-11-12

This study is looking to help people living with HIV in South Africa by providing support for mental health and practical needs, like food, to make it easier for them to stick to their treatment plan.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionMassachusetts General Hospital
NIH-funded
Lab location1 site (Boston, United States)
Project startFebruary 15, 2024
Project endJanuary 31, 2026
Funding year2025
Award (this year)$53,844
NIH project number3K23MH135748-02S1
Project IDNIH-11237402 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are individuals living with HIV in South Africa who are experiencing mental health challenges or social issues that affect their treatment adherence.

Less likely to help

Patients who are not living with HIV or those who do not face psychosocial or structural challenges may not benefit from this research.

What this research studies

This research focuses on developing a comprehensive intervention to support individuals living with HIV in South Africa, addressing both mental health issues like depression and post-traumatic stress, as well as structural challenges such as food insecurity. The approach involves creating a multilevel program that combines psychological support and practical resources to improve adherence to antiretroviral therapy (ART). By understanding how these psychosocial and structural factors interact, the research aims to enhance health outcomes for patients. The intervention will be tested for its acceptability and feasibility among the target population.

Why it matters

Potential benefit: If successful, this research could significantly improve the health and quality of life for people living with HIV by enhancing their adherence to treatment.

How similar studies have gone: Previous research has shown that addressing psychosocial and structural factors can improve health outcomes for individuals with HIV, indicating that this approach has potential for success.

Where this research is happening

  • Massachusetts General Hospital
    Boston, United States
    Active

Researchers

  • Principal investigator: Lee, Jasper Samuel — Massachusetts General Hospital
  • Study coordinator: Lee, Jasper Samuel

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.