Creating a portable tool to assess cognitive decline in Alzheimer's and related dementias
Official title: Development and Evaluation of Portable Compendium of Psychophysical and Physiological Tests for Alzheimer's Disease and Related Dementias (ADRD)
Funded at Evon Medics, LLC · NIH-11143916 · Data updated 2026-11-12
This study is working on a simple digital device that you can use at home or in the office to help track changes in thinking skills as we age, making it easier for doctors to spot early signs of memory problems and provide support when needed.
Quick facts
| Grant type | Sbir 2 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Evon Medics, LLC NIH-funded |
| Lab location | 1 site (Elkridge, United States) |
| Project start | August 1, 2023 |
| Project end | April 30, 2026 |
| Funding year | 2025 |
| Award (this year) | $1,249,244 |
| NIH project number | 5R44AG082621-03 |
| Project ID | NIH-11143916 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include elderly individuals experiencing subjective cognitive impairment or those concerned about age-related cognitive decline.
✕Less likely to help
Patients who are not experiencing any cognitive decline or who have already been diagnosed with advanced dementia may not benefit from this research.
What this research studies
This research aims to develop a user-friendly digital device that can be used at home or in an office setting to assess cognitive decline associated with aging. The device will automate the staging of cognitive impairment and monitor changes over time, helping to identify individuals at risk for progressive neurodegenerative diseases. By providing a reliable method for early detection, the research seeks to improve the ability of healthcare providers to recognize and address cognitive issues in elderly patients. This approach is designed to be culturally valid and accessible to a wide range of users.
Why it matters
Potential benefit: If successful, this research could enable earlier detection of cognitive decline, allowing for timely interventions that may slow the progression of Alzheimer's disease and related dementias.
How similar studies have gone: Other research has shown promise in using digital tools for cognitive assessment, indicating that this approach could be effective in identifying early cognitive decline.
Where this research is happening
-
Evon Medics, LLC
Elkridge, United States Active
Researchers
- Principal investigator: Nwaokobia, Charles Chiedu — Evon Medics, LLC
- Study coordinator: Nwaokobia, Charles Chiedu
Related research
Other NIH-funded projects on the same topics.
-
Understanding how brain activity changes may drive Alzheimer’s disease progression in a mouse model
Researchers are testing how changes in brain signals and protein cleanup processes affect the development of Alzheimer’s disease in mice.
-
Thiamine-boosting therapy for Alzheimer’s: understanding how benfotiamine may reduce harmful AGE in DP patients
A medication-based approach using high-dose vitamin B1 (benfotiamine) is studied to help people with Alzheimer's by reducing harmful sugar-related molecules.
-
Non-invasive tears biomarker for early Alzheimer's in LMICs
A low-cost, tear-based biomarker approach aims to detect early Alzheimer’s disease in older adults in Peru and similar settings.
-
Turning APOE4 into protective APOE2 or APOE3Christchurch to help with Alzheimer’s
A patient-facing explanation of a treatment idea that aims to change a genetic risk factor for Alzheimer's disease in the brain.
-
Telomerase in Alzheimer’s Disease: how aging biology could influence memory and brain health
Researchers are exploring a new brain-aging mechanism linked to telomerase, with potential to slow or modify Alzheimer’s disease in people and improve cognitive function.
-
Biomarkers of Alzheimer’s Disease: Sensory, Motor, and Cognitive Clues
Researchers are testing simple sensory and movement tasks to find early signs of Alzheimer’s disease so they can diagnose and treat people sooner.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.