Creating a platform to compare lung cancer preclinical models
Official title: Construction of A Lung Cancer Preclinical Model Cross-comparison Platform
Funded at Ut Southwestern Medical Center · NIH-10774776 · Data updated 2026-11-12
This study is working on a new tool that combines information from different lung cancer models and patient tumors to help researchers find the best ways to study lung cancer and its treatments, making it easier to understand how tumors behave and how they respond to therapies.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Ut Southwestern Medical Center NIH-funded |
| Lab location | 1 site (Dallas, United States) |
| Project start | September 1, 2024 |
| Project end | August 31, 2029 |
| Funding year | 2024 |
| Award (this year) | $627,833 |
| NIH project number | 1R01CA285336-01 |
| Project ID | NIH-10774776 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are lung cancer patients whose tumors can be compared with preclinical models to improve treatment outcomes.
✕Less likely to help
Patients with cancers other than lung cancer may not receive direct benefits from this research.
What this research studies
This research focuses on developing a comprehensive platform that integrates molecular and pathological data from various lung cancer preclinical models and human tumors. By analyzing existing data and utilizing advanced algorithms, the project aims to identify the most effective preclinical models for studying lung cancer biology and treatment responses. Patients' tumor pathology images will be used to enhance the understanding of tumor characteristics and their implications for therapy. This platform will ultimately help researchers make informed decisions about which models to use for specific scientific inquiries.
Why it matters
Potential benefit: If successful, this research could lead to more effective and personalized treatment strategies for lung cancer patients.
How similar studies have gone: Previous research has shown success in using integrated platforms for cancer analysis, indicating a promising approach for this novel project.
Where this research is happening
-
Ut Southwestern Medical Center
Dallas, United States Active
Researchers
- Principal investigator: Cai, Ling — Ut Southwestern Medical Center
- Study coordinator: Cai, Ling
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.