Creating a platform for manufacturing gene therapies for sickle cell disease

CureSC Manufacturing Resource Platform

['FUNDING_OTHER'] · BECKMAN RESEARCH INSTITUTE/CITY OF HOPE · NIH-10023023

This study is all about finding out what people with sickle cell disease need to help make better gene therapies, so the team can create a plan to improve how these treatments are made and make them more available for patients like you.

Quick facts

Phase['FUNDING_OTHER']
Study typeNih_funding
SexAll
SponsorBECKMAN RESEARCH INSTITUTE/CITY OF HOPE (nih funded)
Locations1 site (DUARTE, UNITED STATES)
Trial IDNIH-10023023 on ClinicalTrials.gov

What this research studies

This research focuses on establishing a manufacturing resource platform aimed at developing curative genetic therapies for sickle cell disease (SCD). The City of Hope team will conduct a needs assessment to understand the specific requirements of the sickle cell community regarding cell and vector product manufacturing. They will evaluate existing manufacturing capabilities and work with various stakeholders to create a strategic plan for a consortium that supports the production of necessary therapies. This initiative aims to enhance the availability and quality of gene therapies for patients with SCD.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals diagnosed with sickle cell disease who may benefit from advanced genetic therapies.

Not a fit: Patients with other blood disorders or those not diagnosed with sickle cell disease may not receive any benefit from this research.

Why it matters

Potential benefit: If successful, this research could significantly improve access to effective gene therapies for patients suffering from sickle cell disease.

How similar studies have performed: Other research initiatives focused on gene therapy for sickle cell disease have shown promising results, indicating that this approach has potential for success.

Where this research is happening

DUARTE, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.