Creating a platform for manufacturing curative therapies for sickle cell disease
CureSC Manufacturing Resource Platform
This study is working to create a helpful resource for making treatments for sickle cell disease by talking to patients and experts to find out what’s needed to improve the production of these therapies.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Beckman Research Institute/city of Hope NIH-funded |
| Lab location | 1 site (Duarte, United States) |
| Project ID | NIH-11194675 on NIH RePORTER |
What this research studies
This research aims to establish a manufacturing resource platform specifically for curative genetic therapies targeting sickle cell disease (SCD). The team at City of Hope will conduct a needs assessment to understand the requirements of the sickle cell community regarding cell and vector product manufacturing. They will evaluate current manufacturing capabilities and develop a strategy for a consortium approach to ensure that the necessary resources are available for effective treatment. This initiative will involve collaboration with various experts and facilities to enhance the production of therapeutic products.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with sickle cell disease who may benefit from advanced genetic therapies.
Not a fit: Patients with other blood disorders or those not diagnosed with sickle cell disease may not receive any benefit from this research.
Why it matters
Potential benefit: If successful, this research could significantly improve access to curative therapies for patients with sickle cell disease.
How similar studies have performed: Previous research has shown promise in developing manufacturing platforms for gene therapies, indicating potential success for this approach.
Where this research is happening
Duarte, United States
- Beckman Research Institute/city of Hope — Duarte, United States (Active)
Researchers
- Principal investigator: Cardoso, Angelo a. — Beckman Research Institute/city of Hope
- Study coordinator: Cardoso, Angelo a.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.