Creating a pig model to study spinal cord tumors
Lentiviral-Induced Swine Model of Spinal Cord Glioma
This study is creating a special minipig model to better understand a rare and aggressive brain tumor called high-grade spinal cord glioma, which could help researchers find better treatments and surgical options for people facing this condition.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Emory University NIH-funded |
| Lab location | 1 site (Atlanta, United States) |
| Project ID | NIH-11084455 on NIH RePORTER |
What this research studies
This research focuses on developing a minipig model of high-grade spinal cord glioma, a rare and aggressive type of brain tumor. By using lentiviral techniques to target specific genetic pathways associated with this cancer, researchers aim to induce tumors that closely mimic those found in humans. The study will evaluate the characteristics of these tumors to improve understanding and treatment options. This model could provide valuable insights into surgical applications and potential therapies for patients suffering from this condition.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with high-grade spinal cord glioma or those at risk for developing this type of tumor.
Not a fit: Patients with other types of tumors or those who do not have spinal cord glioma may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to better treatment options and improved outcomes for patients with spinal cord glioma.
How similar studies have performed: While there have been advancements in animal models for various cancers, this specific approach using minipigs for spinal cord glioma is relatively novel and untested.
Where this research is happening
Atlanta, United States
- Emory University — Atlanta, United States (Active)
Researchers
- Principal investigator: Boulis, Nicholas M — Emory University
- Study coordinator: Boulis, Nicholas M
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.