Creating a personalized model to test drug responses in pancreatic cancer
Personalized Organoid-Chip Model For Drug Testing in Pancreatic Cancer
This study is working on a special tool that helps doctors understand how your unique pancreatic cancer tumor might respond to different treatments, so they can choose the best option just for you.
Quick facts
| Grant type | R21 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Texas Hlth Sci Ctr Houston NIH-funded |
| Lab location | 1 site (Houston, United States) |
| Project ID | NIH-11113431 on NIH RePORTER |
What this research studies
This research aims to develop a personalized platform that predicts how individual pancreatic cancer tumors respond to various treatments. By using 3D patient-derived organoids and advanced microfluidic technologies, the project will create a tumor-chip device that mimics the tumor microenvironment. This device will allow researchers to assess the effectiveness of both conventional and novel therapies on a patient's specific tumor, ultimately guiding personalized treatment decisions. The goal is to enhance the accuracy and reliability of treatment predictions for patients with pancreatic cancer.
Who could benefit from this research
Good fit: Ideal candidates for this research are patients diagnosed with pancreatic cancer who are seeking personalized treatment options.
Not a fit: Patients with cancers other than pancreatic cancer may not benefit from this specific research.
Why it matters
Potential benefit: If successful, this research could lead to more effective and tailored treatment options for patients with pancreatic cancer.
How similar studies have performed: Other research has shown promise in using personalized models for drug testing in various cancers, indicating potential success for this approach.
Where this research is happening
Houston, United States
- University of Texas Hlth Sci Ctr Houston — Houston, United States (Active)
Researchers
- Principal investigator: Bishehsari, Faraz — University of Texas Hlth Sci Ctr Houston
- Study coordinator: Bishehsari, Faraz
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.