Creating a personalized method to map memory in epilepsy patients
Development of a personalized neurostimulation protocol for memory mapping in epilepsy
This study is looking at a new way to use gentle electrical stimulation during memory tests to help doctors understand how to protect memory in people with drug-resistant temporal lobe epilepsy who are having surgery, making sure they have the best chance of keeping their memories after the operation.
Quick facts
| Grant type | Career grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California, San Diego NIH-funded |
| Lab location | 1 site (La Jolla, United States) |
| Project ID | NIH-10754925 on NIH RePORTER |
What this research studies
This research focuses on developing a personalized neurostimulation protocol to help predict memory decline in patients with drug-resistant temporal lobe epilepsy (TLE) who are undergoing surgery. By using electrical stimulation during memory tests, the researchers aim to identify critical brain areas involved in memory function. This innovative approach seeks to improve surgical outcomes by minimizing the risk of memory loss post-surgery. The study will involve mapping the effects of stimulation on memory to ensure precise targeting of brain structures.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with drug-resistant temporal lobe epilepsy who are considering surgical options.
Not a fit: Patients with epilepsy that is well-controlled by medication or those who do not require surgical intervention may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved surgical techniques that preserve memory function in epilepsy patients.
How similar studies have performed: While the approach of using neurostimulation for memory mapping is innovative, similar techniques in related fields have shown promise, indicating potential for success.
Where this research is happening
La Jolla, United States
- University of California, San Diego — La Jolla, United States (Active)
Researchers
- Principal investigator: Kaestner, Erik Jordan — University of California, San Diego
- Study coordinator: Kaestner, Erik Jordan
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.