Creating a personalized implant to restore voice and laryngeal functions
Optimizing a patient-specific regenerative larynx implant for restoration of voice
This study is working on a special implant that’s made just for you to help restore your ability to breathe, swallow, and speak, making everyday life easier and more enjoyable after losing these functions due to health issues.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Mayo Clinic Arizona NIH-funded |
| Lab location | 1 site (Scottsdale, United States) |
| Project ID | NIH-10894917 on NIH RePORTER |
What this research studies
This research focuses on developing a bioengineered implant specifically designed for each patient to restore essential laryngeal functions such as breathing, swallowing, and voice. The project aims to optimize the design and integration of this implant to ensure it fits seamlessly within the patient's anatomy, reducing the need for future surgeries and enhancing healing. By utilizing advanced biomedical engineering techniques, the researchers will evaluate the effectiveness of the implant in restoring normal laryngeal functions, which are crucial for daily life and social interactions. The ultimate goal is to improve the quality of life for patients who have lost these functions due to various medical conditions.
Who could benefit from this research
Good fit: Ideal candidates for this research are children and young adults who have experienced laryngeal damage or dysfunction and are seeking restoration of their voice and related functions.
Not a fit: Patients with intact laryngeal functions or those who do not require surgical intervention for laryngeal issues may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could enable patients to regain their natural voice and improve their ability to breathe and swallow, significantly enhancing their quality of life.
How similar studies have performed: Previous research in bioengineering and regenerative medicine has shown promise in developing similar implants, indicating a potential for success in this novel approach.
Where this research is happening
Scottsdale, United States
- Mayo Clinic Arizona — Scottsdale, United States (Active)
Researchers
- Principal investigator: Lott, David G — Mayo Clinic Arizona
- Study coordinator: Lott, David G
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.