Creating a non-invasive test to detect gestational diabetes early
Official title: Development and Validation of a Non-Invasive Microbiome-Based Diagnostic Tool for Early Detection of Gestational Diabetes Mellitus
Funded at Brooklyn Innoseq INC. · NIH-10921940 · Data updated 2026-11-12
This study is working on a new, easy test that looks at the bacteria in the gut of pregnant women to find out if they might have gestational diabetes earlier than current methods, helping moms-to-be get the care they need sooner.
Quick facts
| Grant type | Sbir 1 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Brooklyn Innoseq INC. NIH-funded |
| Lab location | 1 site (Brooklyn, UNITED STATES) |
| Project start | July 22, 2024 |
| Project end | June 30, 2025 |
| Funding year | 2024 |
| Award (this year) | $296,351 |
| NIH project number | 1R43HD115494-01 |
| Project ID | NIH-10921940 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are pregnant women, particularly those in their first or second trimester, who may be at risk for developing gestational diabetes.
✕Less likely to help
Patients who are not pregnant or those who have already been diagnosed with gestational diabetes may not benefit from this research.
What this research studies
This research focuses on developing a microbial screening test that can detect gestational diabetes mellitus (GDM) earlier than current methods. By analyzing the microbiome of pregnant women, the study aims to identify specific microbial biomarkers associated with GDM. This innovative approach utilizes machine learning technologies to enhance the accuracy of predictions, allowing for earlier intervention and management of diabetes during pregnancy. The test is designed to be non-invasive, making it more accessible for expectant mothers.
Why it matters
Potential benefit: If successful, this research could lead to earlier detection and prevention of gestational diabetes, improving health outcomes for both mothers and their babies.
How similar studies have gone: While the approach of using microbiome profiling for early detection of GDM is innovative, similar methodologies have shown promise in other areas of diabetes research.
Where this research is happening
-
Brooklyn Innoseq INC.
Brooklyn, United States Active
Researchers
- Principal investigator: Fan, Nini — Brooklyn Innoseq INC.
- Study coordinator: Fan, Nini
Related research
Other NIH-funded projects on the same topics.
-
In Vivo Look at Placental Blood Flow in Gestational Diabetes
A non-invasive MRI study in pregnant people with gestational diabetes and those without will map how placental blood vessels work and relate to baby outcomes.
-
Decoding how gestational diabetes links to future coronary artery disease
A study using health records and big data to understand why women who had gestational diabetes later face heart disease, with the goal of guiding prevention.
-
Understanding how gestational diabetes and depression during pregnancy affect mothers and their children
This project explores how gestational diabetes and depression during pregnancy might influence a mother's mental health after birth and her child's brain development.
-
Better Blood Sugar Goals for Pregnant Women with Gestational Diabetes Who Are Overweight or Obese
This project looks at whether stricter blood sugar goals can help pregnant women who have gestational diabetes and are also overweight or obese have healthier pregnancies and babies.
-
Understanding how gestational diabetes develops during pregnancy
This study is looking at how the body's insulin-producing cells change in pregnant women to better understand gestational diabetes and help improve diabetes care for moms both during and after pregnancy.
-
The effects of gestational diabetes and maternal depression on child development
This study looks at how having gestational diabetes and feeling depressed during pregnancy might affect how children develop, and it’s for moms-to-be who want to understand how their health can impact their little ones.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.