Creating a new way to measure recovery for patients with acute respiratory failure
Official title: Developing and Evaluating Quality-Weighted Hospital-Free Days as a Novel, Patient-Centered Outcome for Trials of Patients with Acute Respiratory Failure
Funded at University of Pennsylvania · NIH-10907774 · Data updated 2026-11-12
This study is looking to create a better way to understand how well people recover after experiencing serious breathing problems, by focusing not just on how many days they spend out of the hospital, but also on how they feel and function in their daily lives.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Pennsylvania NIH-funded |
| Lab location | 1 site (Philadelphia, United States) |
| Project start | August 5, 2022 |
| Project end | July 31, 2027 |
| Funding year | 2024 |
| Award (this year) | $191,391 |
| NIH project number | 5K23HL163402-03 |
| Project ID | NIH-10907774 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are adults aged 21 and older who have experienced acute respiratory failure and are currently receiving follow-up care.
✕Less likely to help
Patients who are not experiencing acute respiratory failure or those who are younger than 21 years old may not benefit from this research.
What this research studies
This research focuses on improving the way we measure recovery for patients who have experienced acute respiratory failure (ARF). It aims to develop a new outcome measure called quality-weighted hospital-free days, which takes into account not just the number of days spent outside the hospital, but also the patient's functional status and quality of life. By using patient-reported assessments, the study seeks to create a more comprehensive understanding of recovery that reflects the real experiences of patients and their caregivers. The research will involve training in advanced study design and statistical methods to ensure robust results.
Why it matters
Potential benefit: If successful, this research could lead to a more accurate and meaningful way to evaluate recovery for patients with acute respiratory failure, ultimately improving their long-term outcomes.
How similar studies have gone: Previous research has shown success in using hospital-free days as an outcome measure in other acute illness populations, but this specific approach for ARF is novel.
Where this research is happening
-
University of Pennsylvania
Philadelphia, United States Active
Researchers
- Principal investigator: Auriemma, Catherine Louise — University of Pennsylvania
- Study coordinator: Auriemma, Catherine Louise
Related research
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A study will test a quick, noninvasive breathing test called oscillometry to see how well children who survived dangerous lung problems recover over time.
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This research looks at how a person's own breathing effort affects lung and diaphragm injury for adults on ventilators for acute respiratory failure.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.