Creating a new way to measure recovery for patients with acute respiratory failure

Developing and Evaluating Quality-Weighted Hospital-Free Days as a Novel, Patient-Centered Outcome for Trials of Patients with Acute Respiratory Failure

NIH-funded research University of Pennsylvania · NIH-10907774

This study is looking to create a better way to understand how well people recover after experiencing serious breathing problems, by focusing not just on how many days they spend out of the hospital, but also on how they feel and function in their daily lives.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionUniversity of Pennsylvania NIH-funded
Lab location1 site (Philadelphia, United States)
Project IDNIH-10907774 on NIH RePORTER

What this research studies

This research focuses on improving the way we measure recovery for patients who have experienced acute respiratory failure (ARF). It aims to develop a new outcome measure called quality-weighted hospital-free days, which takes into account not just the number of days spent outside the hospital, but also the patient's functional status and quality of life. By using patient-reported assessments, the study seeks to create a more comprehensive understanding of recovery that reflects the real experiences of patients and their caregivers. The research will involve training in advanced study design and statistical methods to ensure robust results.

Who could benefit from this research

Good fit: Ideal candidates for this research are adults aged 21 and older who have experienced acute respiratory failure and are currently receiving follow-up care.

Not a fit: Patients who are not experiencing acute respiratory failure or those who are younger than 21 years old may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to a more accurate and meaningful way to evaluate recovery for patients with acute respiratory failure, ultimately improving their long-term outcomes.

How similar studies have performed: Previous research has shown success in using hospital-free days as an outcome measure in other acute illness populations, but this specific approach for ARF is novel.

Where this research is happening

Philadelphia, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.