Creating a new way to diagnose idiopathic hypersomnia using sleep patterns
Development and Validation of a Nocturnal Sleep Signature for the Diagnosis of Idiopathic Hypersomnia
This study is looking to find a new way to diagnose idiopathic hypersomnia, a condition that makes you feel really sleepy during the day, by identifying specific biological markers in your sleep patterns, so that people can get the right help more easily.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Boston Children's Hospital NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project ID | NIH-11083750 on NIH RePORTER |
What this research studies
This research aims to develop and validate a new biomarker signature for diagnosing idiopathic hypersomnia (IH), a condition that causes excessive sleepiness and typically begins in adolescence. The current diagnostic method, multiple sleep latency testing (MSLT), is not effective for IH, leading to misdiagnosis and challenges in treatment. By analyzing sleep patterns, particularly during the night, the research team hopes to identify specific biological markers that can accurately reflect the presence of IH. This approach involves a multi-disciplinary team with expertise in neurophysiology and biomarker discovery, focusing on improving diagnostic accuracy for affected individuals.
Who could benefit from this research
Good fit: Ideal candidates for this research are adolescents aged 12 to 20 who experience excessive daytime sleepiness and may have idiopathic hypersomnia.
Not a fit: Patients who do not fall within the adolescent age range or who have other sleep disorders unrelated to idiopathic hypersomnia may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more accurate diagnoses of idiopathic hypersomnia, allowing for better-targeted treatments and improved quality of life for patients.
How similar studies have performed: Previous research has shown promise in developing biomarkers for sleep disorders, but this specific approach for idiopathic hypersomnia is novel and untested.
Where this research is happening
Boston, United States
- Boston Children's Hospital — Boston, United States (Active)
Researchers
- Principal investigator: Maski, Kiran Prasad — Boston Children's Hospital
- Study coordinator: Maski, Kiran Prasad
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.