Creating a new vaccine to prevent tuberculosis
Official title: Development of an Optimized Adjuvanted TB Vaccine
Funded at University of Montana · NIH-11192732 · Data updated 2026-11-12
This study is working on a better vaccine for tuberculosis (TB) that uses special ingredients to help your immune system fight the disease, and it will be given either as a shot or a nasal spray to help protect people from getting TB.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Montana NIH-funded |
| Lab location | 1 site (Missoula, United States) |
| Project start | September 30, 2021 |
| Project end | September 30, 2025 |
| Funding year | 2024 |
| Award (this year) | $253,399 |
| NIH project number | 75N93019C00045-P00023-9999-3 |
| Project ID | NIH-11192732 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals at high risk of tuberculosis infection, including those in endemic areas or with compromised immune systems.
✕Less likely to help
Patients who are already infected with tuberculosis or those who have previously received a TB vaccine may not benefit from this research.
What this research studies
This research focuses on developing an improved vaccine for tuberculosis (TB) that uses specific adjuvants to enhance the immune response. The vaccine will be administered either through injection or nasal spray and will incorporate advanced TB antigens to boost its effectiveness. By optimizing the formulation, the researchers aim to create a more effective preventive measure against TB, which is a significant global health concern.
Why it matters
Potential benefit: If successful, this research could lead to a more effective vaccine that significantly reduces the incidence of tuberculosis.
How similar studies have gone: Other research has shown promise in developing adjuvanted vaccines for various infections, suggesting that this approach could be effective for tuberculosis as well.
Where this research is happening
-
University of Montana
Missoula, United States Active
Researchers
- Principal investigator: Evans, Jay — University of Montana
- Study coordinator: Evans, Jay
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.