Creating a new treatment to improve vaginal health after menopause
Developing a nonsteroidal and nonhormonal agent that reverses menopause-related loss of genital epithelial integrity and function
This study is testing a new, non-hormonal treatment for postmenopausal women experiencing vaginal discomfort due to menopause, using a special peptide to help improve vaginal health and comfort over time.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Ohio State University NIH-funded |
| Lab location | 1 site (Columbus, UNITED STATES) |
| Project ID | NIH-10901049 on NIH RePORTER |
What this research studies
This research focuses on developing a nonsteroidal and nonhormonal treatment to address the genitourinary syndrome of menopause (GSM), which affects many postmenopausal women. The study aims to restore the integrity and function of genital epithelial tissue that deteriorates due to lower estrogen levels. By using a specially designed peptide administered intravaginally, the research will evaluate its effectiveness in improving vaginal health and safety over long-term use. The approach is based on previous findings that showed promise in animal models.
Who could benefit from this research
Good fit: Ideal candidates for this research are postmenopausal women experiencing symptoms of genitourinary syndrome.
Not a fit: Patients who are not postmenopausal or do not experience symptoms related to genitourinary syndrome may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could provide a safer alternative treatment for postmenopausal women suffering from vaginal irritation and related symptoms.
How similar studies have performed: Previous research has shown success with similar approaches in animal models, but this specific treatment is novel and untested in humans.
Where this research is happening
Columbus, UNITED STATES
- Ohio State University — Columbus, United States (Active)
Researchers
- Principal investigator: Cherpes, Thomas L. — Ohio State University
- Study coordinator: Cherpes, Thomas L.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.