Creating a new treatment to eliminate brain cancer and its spread.
Official title: Developing a Novel Biologic Therapy to Eradicate Brain Cancer and Brain Metastasis
Funded at Creative Biotherapeutics, LLC · NIH-11007080 · Data updated 2026-11-12
This study is testing a new treatment for brain cancer that aims to help patients, both adults and kids, who haven't had success with current therapies by targeting specific pathways in their tumors.
Quick facts
| Grant type | Sbir 1 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Creative Biotherapeutics, LLC NIH-funded |
| Lab location | 1 site (Gurnee, United States) |
| Project start | September 1, 2024 |
| Project end | August 31, 2025 |
| Funding year | 2024 |
| Award (this year) | $400,000 |
| NIH project number | 1R43CA295180-01 |
| Project ID | NIH-11007080 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include patients of all ages diagnosed with primary or secondary brain cancers that are resistant to current therapies.
✕Less likely to help
Patients with brain cancers that are not drug-resistant or those who have not been diagnosed with brain tumors may not benefit from this research.
What this research studies
This research focuses on developing a novel biologic therapy aimed at eradicating brain cancer and brain metastasis, particularly in patients who have not responded to existing treatments. The approach involves targeting specific survival pathways that are upregulated in recurrent drug-resistant brain tumors. By utilizing innovative biological therapies, the research aims to provide a more effective treatment option for patients suffering from these aggressive cancers. The study will involve both adult and pediatric populations, addressing a critical need for new therapies in this area.
Why it matters
Potential benefit: If successful, this research could provide a groundbreaking treatment option for patients with resistant brain cancers, potentially improving survival rates and quality of life.
How similar studies have gone: While there have been numerous studies on brain cancer treatments, this specific approach targeting drug-resistant tumors is novel and has not been extensively tested.
Where this research is happening
-
Creative Biotherapeutics, LLC
Gurnee, United States Active
Researchers
- Principal investigator: Davidson, Donald — Creative Biotherapeutics, LLC
- Study coordinator: Davidson, Donald
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.