Creating a new tool to measure physical function in people with multiple sclerosis

Who could benefit from this research

What this research studies

This research aims to develop a comprehensive qualification package for a new patient-reported outcome measure specifically designed for individuals with multiple sclerosis (MS). The focus is on creating a reliable and valid tool that reflects the physical functioning of MS patients, which can be used in drug development and clinical assessments. By gathering quantitative evidence and submitting this to the FDA, the researchers hope to ensure that this measure is recognized as suitable for evaluating the impact of treatments on physical function in MS. This initiative is driven by the need for a standardized approach that incorporates the patient perspective in assessing their health-related quality of life.

Why it matters

Where this research is happening

• Critical Path Institute
  Tucson, United States Active

Researchers

• Principal investigator: Eremenco, Sonya — Critical Path Institute
• Study coordinator: Eremenco, Sonya

Related research

Other NIH-funded projects on the same topics.

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• Astrocyte exosomes as aging biomarkers and drivers of MS progression

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  NIH research Yale University · New Haven, United States · NIH-11448588

• Promoting brain repair in MS with a natural compound that nudges neural stem cells

  A researcher is testing a natural-product–based compound that may help people with multiple sclerosis repair nerve damage by guiding brain stem cells to become neurons and myelin-producing cells.

  NIH research University of Illinois at Urbana-Champaign · Champaign, United States · NIH-11443028

• Targeted B cell tolerance therapy for multiple sclerosis using Ace-DEX microparticles

  A new therapy using tiny biopolymer particles given through the vein aims to retrain B cells to tolerate the immune system in people with multiple sclerosis.

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About this research

1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.