Creating a new tool to measure fatigue in people with multiple sclerosis

Development of a Full Qualification Package for the PROMIS Short Form v1.0—Fatigue-Multiple Sclerosis 8a (DDT COA #000069)

['FUNDING_U01'] · CRITICAL PATH INSTITUTE · NIH-10617072

This study is working on a new tool to help measure how tired people with multiple sclerosis feel, so that it can be used to improve treatments and support for those living with the condition.

Quick facts

Phase['FUNDING_U01']
Study typeNih_funding
SexAll
SponsorCRITICAL PATH INSTITUTE (nih funded)
Locations1 site (TUCSON, UNITED STATES)
Trial IDNIH-10617072 on ClinicalTrials.gov

What this research studies

This research focuses on developing a reliable tool to measure fatigue severity specifically for individuals with multiple sclerosis (MS). The team aims to create a Full Qualification Package for the PROMIS Fatigue-Multiple Sclerosis 8a, which will be submitted to the FDA for recognition as a valid patient-reported outcome measure. By gathering evidence and feedback from patients, the research seeks to ensure that the tool accurately reflects the experiences of those living with MS-related fatigue. This will ultimately aid in drug development and improve treatment options for patients.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals diagnosed with any form of multiple sclerosis who experience significant fatigue.

Not a fit: Patients without a diagnosis of multiple sclerosis or those who do not experience fatigue may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could provide a standardized way to assess fatigue in MS patients, leading to better-targeted treatments and improved quality of life.

How similar studies have performed: Previous research has successfully developed patient-reported outcome measures for other conditions, suggesting a strong potential for this approach in the context of multiple sclerosis.

Where this research is happening

TUCSON, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.