Creating a new tool to measure fatigue in people with multiple sclerosis
Official title: Development of a Full Qualification Package for the PROMIS Short Form v1.0—Fatigue-Multiple Sclerosis 8a (DDT COA #000069)
Funded at Critical Path Institute · NIH-10617072 · Data updated 2026-11-12
This study is working on a new tool to help measure how tired people with multiple sclerosis feel, so that it can be used to improve treatments and support for those living with the condition.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Critical Path Institute NIH-funded |
| Lab location | 1 site (Tucson, United States) |
| Project start | September 15, 2022 |
| Project end | August 31, 2025 |
| Funding year | 2022 |
| Award (this year) | $249,989 |
| NIH project number | 1U01FD007765-01 |
| Project ID | NIH-10617072 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals diagnosed with any form of multiple sclerosis who experience significant fatigue.
✕Less likely to help
Patients without a diagnosis of multiple sclerosis or those who do not experience fatigue may not benefit from this research.
What this research studies
This research focuses on developing a reliable tool to measure fatigue severity specifically for individuals with multiple sclerosis (MS). The team aims to create a Full Qualification Package for the PROMIS Fatigue-Multiple Sclerosis 8a, which will be submitted to the FDA for recognition as a valid patient-reported outcome measure. By gathering evidence and feedback from patients, the research seeks to ensure that the tool accurately reflects the experiences of those living with MS-related fatigue. This will ultimately aid in drug development and improve treatment options for patients.
Why it matters
Potential benefit: If successful, this research could provide a standardized way to assess fatigue in MS patients, leading to better-targeted treatments and improved quality of life.
How similar studies have gone: Previous research has successfully developed patient-reported outcome measures for other conditions, suggesting a strong potential for this approach in the context of multiple sclerosis.
Where this research is happening
-
Critical Path Institute
Tucson, United States Active
Researchers
- Principal investigator: Eremenco, Sonya — Critical Path Institute
- Study coordinator: Eremenco, Sonya
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.