Creating a new tool for growing and testing human organ-like tissues
Programmable Microfluidic Perfusion Bioreactor for 3D Organoid Culture and Screening Applications
This study is working on a special device that helps scientists grow tiny models of human organs to test new medicines, which could lead to safer and more effective treatments for patients like you, while using fewer animals in research.
Quick facts
| Grant type | Sbir 1 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Mosaic Engineering LLC NIH-funded |
| Lab location | 1 site (Richmond, United States) |
| Project ID | NIH-10821563 on NIH RePORTER |
What this research studies
This research focuses on developing a programmable microfluidic perfusion bioreactor that allows for the culture and screening of 3D organoids, which are miniature versions of human organs. By using pluripotent stem cells, the project aims to create more accurate models for drug testing, reducing reliance on animal testing. The bioreactor will enable researchers to grow these organoids in a controlled environment, facilitating better drug discovery and development processes. Patients may benefit from more effective and safer drugs as a result of this innovative approach.
Who could benefit from this research
Good fit: Ideal candidates for participation or benefit from this research include individuals interested in advancements in drug therapies and those affected by conditions that require innovative treatment options.
Not a fit: Patients who are not seeking new drug therapies or who are not affected by conditions relevant to the organoids being developed may not receive direct benefits from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective and safer drug treatments for patients.
How similar studies have performed: Other research has shown success with similar organoid models in drug testing, indicating a promising direction for this innovative approach.
Where this research is happening
Richmond, United States
- Mosaic Engineering LLC — Richmond, United States (Active)
Researchers
- Principal investigator: Myers, Frank — Mosaic Engineering LLC
- Study coordinator: Myers, Frank
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.