Creating a new tool for growing and testing 3D organoids
Official title: Programmable Microfluidic Perfusion Bioreactor for 3D Organoid Culture and Screening Applications
Funded at Mosaic Engineering LLC · NIH-11270625 · Data updated 2026-11-12
This study is working on a new tool that helps scientists grow tiny versions of organs to test how well new drugs work, especially for heart health, which could lead to better treatments for people without needing to rely as much on animal testing.
Quick facts
| Grant type | Sbir 1 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Mosaic Engineering LLC NIH-funded |
| Lab location | 1 site (Richmond, United States) |
| Project start | February 1, 2024 |
| Project end | October 31, 2025 |
| Funding year | 2025 |
| Award (this year) | $55,000 |
| NIH project number | 3R43HL172397-01S1 |
| Project ID | NIH-11270625 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals with cardiovascular conditions who may benefit from new drug therapies.
✕Less likely to help
Patients who do not have cardiovascular issues or are not involved in drug development processes may not receive direct benefits from this research.
What this research studies
This research focuses on developing a programmable microfluidic perfusion bioreactor that allows for the growth and testing of 3D organoids, which are miniaturized and simplified versions of organs. By using this innovative platform, researchers aim to create a more accurate and cost-effective method for drug screening, potentially reducing the reliance on traditional animal models. The project will involve building automation software and demonstrating how these organoids can respond to drug treatments, particularly in the context of cardiac health. This approach could lead to more successful drug development processes by providing better predictive models for human responses.
Why it matters
Potential benefit: If successful, this research could lead to more effective drug development and safer treatments for patients.
How similar studies have gone: Other research has shown promise in using organoids for drug testing, indicating that this approach could be a significant advancement in the field.
Where this research is happening
-
Mosaic Engineering LLC
Richmond, United States Active
Researchers
- Principal investigator: Myers, Frank — Mosaic Engineering LLC
- Study coordinator: Myers, Frank
Related research
Other NIH-funded projects on the same topics.
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Creating a new tool for growing and testing human organ-like tissues
This study is working on a special device that helps scientists grow tiny models of human organs to test new medicines, which could lead to safer and more effective treatments for patients like you, while using fewer animals in research.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.