Creating a new tool for growing and testing 3D organoids
Programmable Microfluidic Perfusion Bioreactor for 3D Organoid Culture and Screening Applications
This study is working on a new tool that helps scientists grow tiny versions of organs to test how well new drugs work, especially for heart health, which could lead to better treatments for people without needing to rely as much on animal testing.
Quick facts
| Grant type | Sbir 1 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Mosaic Engineering LLC NIH-funded |
| Lab location | 1 site (Richmond, United States) |
| Project ID | NIH-11270625 on NIH RePORTER |
What this research studies
This research focuses on developing a programmable microfluidic perfusion bioreactor that allows for the growth and testing of 3D organoids, which are miniaturized and simplified versions of organs. By using this innovative platform, researchers aim to create a more accurate and cost-effective method for drug screening, potentially reducing the reliance on traditional animal models. The project will involve building automation software and demonstrating how these organoids can respond to drug treatments, particularly in the context of cardiac health. This approach could lead to more successful drug development processes by providing better predictive models for human responses.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with cardiovascular conditions who may benefit from new drug therapies.
Not a fit: Patients who do not have cardiovascular issues or are not involved in drug development processes may not receive direct benefits from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective drug development and safer treatments for patients.
How similar studies have performed: Other research has shown promise in using organoids for drug testing, indicating that this approach could be a significant advancement in the field.
Where this research is happening
Richmond, United States
- Mosaic Engineering LLC — Richmond, United States (Active)
Researchers
- Principal investigator: Myers, Frank — Mosaic Engineering LLC
- Study coordinator: Myers, Frank
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.