Creating a new tool for analyzing biological samples using mass spectrometry
Development of VSSI-probe technology for in situ probing biological systems using mass spectrometry
['FUNDING_R01'] · WEST VIRGINIA UNIVERSITY · NIH-10687118
This study is working on a new tool that helps scientists quickly and safely analyze living cells and tissues, which could improve our understanding of diseases like Huntington's disease and make research easier for everyone.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | WEST VIRGINIA UNIVERSITY (nih funded) |
| Locations | 1 site (MORGANTOWN, UNITED STATES) |
| Trial ID | NIH-10687118 on ClinicalTrials.gov |
What this research studies
This research focuses on developing a new technology called the vibrating sharp-edge spray ionization probe (VSSI-probe) that allows for direct analysis of biological samples in their natural state. By improving mass spectrometry techniques, the VSSI-probe aims to make it easier and faster to study living cells and tissues without damaging them. This innovative approach could lead to significant advancements in understanding various biological processes and diseases, including Huntington's disease. The research emphasizes creating a user-friendly and cost-effective tool that can be widely adopted in biological studies.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals affected by conditions that require detailed biological analysis, such as Huntington's disease.
Not a fit: Patients with conditions that do not involve biological sample analysis or those who are not undergoing treatment that requires such analysis may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could provide a groundbreaking method for real-time analysis of biological systems, leading to better diagnosis and treatment options for patients.
How similar studies have performed: Other research has shown promise in developing advanced mass spectrometry techniques, but the VSSI-probe represents a novel approach that has not been extensively tested.
Where this research is happening
MORGANTOWN, UNITED STATES
- WEST VIRGINIA UNIVERSITY — MORGANTOWN, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: LI, PENG — WEST VIRGINIA UNIVERSITY
- Study coordinator: LI, PENG
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.