Creating a new test to quickly assess radiation exposure and injury after nuclear events
Development of FAST-DOSE assay system for the rapid assessment of acute radiation exposure, individual radiosensitivity and injury in victims for a large-scale radiological incident
This study is testing a new quick test called FAST-DOSE that helps doctors figure out how much radiation someone has been exposed to after an emergency, using samples like blood or urine, so they can provide the right care as soon as possible.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Columbia University Health Sciences NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project ID | NIH-11009617 on NIH RePORTER |
What this research studies
This research focuses on developing a rapid assay system called FAST-DOSE to evaluate the effects of acute radiation exposure on individuals following a large-scale radiological incident. By analyzing human biofluids such as blood, urine, and saliva within the first week after exposure, the study aims to provide accurate predictions of radiation doses and facilitate timely medical management. The FAST-DOSE system utilizes advanced imaging technology to measure specific proteins and biomarkers in blood samples, which can indicate the level of radiation exposure and potential injury. This innovative approach is designed to enhance triage decisions and improve patient outcomes in emergency situations.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals who have been exposed to ionizing radiation during a large-scale radiological event.
Not a fit: Patients who have not been exposed to radiation or are not involved in a radiological incident may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to faster and more accurate assessments of radiation exposure, improving medical care for victims of nuclear incidents.
How similar studies have performed: Other research has shown promise in developing biodosimetry devices for radiation exposure assessment, indicating that this approach has potential for success.
Where this research is happening
New York, United States
- Columbia University Health Sciences — New York, United States (Active)
Researchers
- Principal investigator: Turner, Helen C — Columbia University Health Sciences
- Study coordinator: Turner, Helen C
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.