Creating a new test to quickly assess radiation exposure and injury after a nuclear event

Development of FAST-DOSE assay system for the rapid assessment of acute radiation exposure, individual radiosensitivity and injury in victims for a large-scale radiological incident

NIH-funded research Columbia University Health Sciences · NIH-10768565

This study is working on a new test called the FAST-DOSE assay that quickly checks how much radiation someone has been exposed to after a big accident, using samples like blood or urine, to help doctors make the best treatment decisions right away.

Quick facts

Grant typeU01 cooperative agreement
Study typeNIH-funded research
Funding institutionColumbia University Health Sciences NIH-funded
Lab location1 site (New York, United States)
Project IDNIH-10768565 on NIH RePORTER

What this research studies

This research focuses on developing the FAST-DOSE assay system, which aims to rapidly assess the level of radiation exposure in individuals following a large-scale radiological incident. By analyzing human biofluids like blood, urine, and saliva within the first week after exposure, the system can provide accurate predictions of radiation dose and help in making timely medical decisions. The assay utilizes advanced imaging technology to measure specific proteins and biomarkers that indicate radiation sensitivity and injury, facilitating effective triage and treatment.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals who have been exposed to ionizing radiation due to a nuclear or radiological incident.

Not a fit: Patients who have not been exposed to radiation or are not involved in a radiological incident may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could significantly improve the management and treatment of individuals exposed to harmful radiation during emergencies.

How similar studies have performed: Other research has shown promise in developing biodosimetry devices, but the FAST-DOSE assay represents a novel approach with specific advancements in high-throughput analysis.

Where this research is happening

New York, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-10 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.