Creating a new technology to discover natural products more efficiently
Development and validation of a high-throughput MicroED-driven platform technology for natural product discovery
This study is working on a new way to quickly find and understand the helpful ingredients in natural products, which could lead to new treatments for different health issues that might help patients like you.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Emory University NIH-funded |
| Lab location | 1 site (Atlanta, United States) |
| Project ID | NIH-11032895 on NIH RePORTER |
What this research studies
This research focuses on developing a high-throughput platform that utilizes micro-crystal electron diffraction (MicroED) to identify and analyze the active components in natural products. By overcoming traditional challenges in structural elucidation, such as insufficient material for analysis and limitations of existing methods, this innovative approach aims to enhance the discovery of bioactive compounds. Patients may benefit from new treatments derived from these natural products, which could address various health conditions.
Who could benefit from this research
Good fit: Ideal candidates for participation or benefit from this research include individuals with conditions that could be treated by new natural products, such as infections or chronic diseases.
Not a fit: Patients with conditions that do not respond to natural product therapies may not receive any benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to the discovery of new natural products that may provide effective treatments for various diseases.
How similar studies have performed: Other research has shown promise in using advanced techniques like cryo-electron microscopy for structural analysis, indicating potential success for this novel approach.
Where this research is happening
Atlanta, United States
- Emory University — Atlanta, United States (Active)
Researchers
- Principal investigator: Quave, Cassandra Leah — Emory University
- Study coordinator: Quave, Cassandra Leah
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.