Creating a new survey to detect nerve damage from chemotherapy in young children
Official title: Development of a novel survey to screen for chemotherapy-induced peripheral neuropathy in young children
Funded at Yale University · NIH-10981754 · Data updated 2026-11-12
This study is creating a new survey to help find out if young children with leukemia are experiencing nerve pain from their chemotherapy, so we can better support their health and well-being after treatment.
Quick facts
| Grant type | Career grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Yale University NIH-funded |
| Lab location | 1 site (New Haven, United States) |
| Project start | September 1, 2024 |
| Project end | August 31, 2029 |
| Funding year | 2024 |
| Award (this year) | $255,769 |
| NIH project number | 1K08CA286835-01A1 |
| Project ID | NIH-10981754 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are children aged 0-11 years who are receiving or have received chemotherapy for cancer, particularly acute lymphoblastic leukemia.
✕Less likely to help
Patients who are not undergoing chemotherapy or who are older than 11 years may not benefit from this research.
What this research studies
This research aims to develop a novel survey that will help identify chemotherapy-induced peripheral neuropathy (CIPN) in young children, particularly those undergoing treatment for acute lymphoblastic leukemia. The project will involve training in qualitative research and survey development, allowing the principal investigator to create a reliable tool for screening this debilitating side effect. By collaborating with a multidisciplinary team, the research will focus on understanding the symptoms and impacts of CIPN on children's development and quality of life. The ultimate goal is to improve the health outcomes for childhood cancer survivors by implementing effective screening methods.
Why it matters
Potential benefit: If successful, this research could lead to better detection and management of nerve damage in children undergoing cancer treatment, improving their long-term health and quality of life.
How similar studies have gone: Previous research has shown success in developing screening tools for treatment-related side effects in pediatric populations, indicating that this approach has potential.
Where this research is happening
-
Yale University
New Haven, United States Active
Researchers
- Principal investigator: Rodwin, Rozalyn — Yale University
- Study coordinator: Rodwin, Rozalyn
Related research
Other NIH-funded projects on the same topics.
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Non-invasive, microscopic biomarkers to detect CIPN in chemotherapy patients
This grant aims to develop a non-invasive imaging method to measure nerve changes in patients undergoing chemotherapy to better understand and monitor chemotherapy-induced peripheral neuropathy (CIPN).
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Longitudinal study of how body-sense relates to chemotherapy nerve damage
This study follows people with breast or gastrointestinal cancer and healthy controls to see if brain processing of body sensations contributes to chemotherapy-induced nerve damage.
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A new screen for chemotherapy-related nerve problems in young children
A clinician-scientist at Yale is developing a child-friendly survey to quickly screen for nerve-related side effects from cancer treatment in kids from birth to age 5.
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How the immune system’s CD4+ T cells in women might prevent chemotherapy-related nerve pain
A study in mice explores whether female immune cells in nerve tissue can lessen pain from chemotherapy, with potential implications for preventing CIPN in women.
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Axonal transport and chemotherapy-related nerve pain
This grant studies why certain cancer patients develop painful nerve damage from chemotherapy and explores ways to prevent or treat it.
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Remote monitoring and nurse follow-up to manage chemotherapy-induced peripheral neuropathy
A program uses symptom reporting tools with nurse follow-up to reduce and better manage chemotherapy-induced neuropathy for cancer survivors, during and after treatment.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.