Creating a new rat model to test anti-aging treatments
A New Translational Rat Model for Evaluating Anti-Aging Interventions
['FUNDING_OTHER'] · UNIVERSITY OF OKLAHOMA HLTH SCIENCES CTR · NIH-11083189
This study is creating a special type of lab rat that ages like humans do, so researchers can test different treatments to help people live longer and healthier lives as they get older.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF OKLAHOMA HLTH SCIENCES CTR (nih funded) |
| Locations | 1 site (OKLAHOMA CITY, UNITED STATES) |
| Trial ID | NIH-11083189 on ClinicalTrials.gov |
What this research studies
This research focuses on developing a unique laboratory rat model that mimics human aging more closely than traditional mouse models. The rats will be genetically diverse and will allow researchers to evaluate various interventions aimed at extending lifespan and improving health in aging. By studying the effects of specific treatments, such as 17α-estradiol, on these rats, the research aims to uncover insights that could lead to better anti-aging therapies for humans. Patients may benefit from the findings as they could inform future treatments for age-related conditions.
Who could benefit from this research
Good fit: Ideal candidates for participation or benefit from this research would be individuals interested in age-related health interventions or those affected by age-related diseases.
Not a fit: Patients with acute conditions unrelated to aging or those who are not interested in anti-aging interventions may not receive any benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new therapies that enhance longevity and health in aging populations.
How similar studies have performed: Previous research using similar approaches with genetically diverse animal models has shown promise, indicating potential for success in this novel application.
Where this research is happening
OKLAHOMA CITY, UNITED STATES
- UNIVERSITY OF OKLAHOMA HLTH SCIENCES CTR — OKLAHOMA CITY, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: RICHARDSON, ARLAN G. — UNIVERSITY OF OKLAHOMA HLTH SCIENCES CTR
- Study coordinator: RICHARDSON, ARLAN G.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Alzheimer disease dementia, Alzheimer syndrome, Alzheimer's Disease