Creating a new platform to treat brain tumors using advanced imaging and heating techniques
Official title: Development of a prototype clinical theranostic platform combining Magnetic Particle Imaging (MPI) and Magnetic Fluid Hyperthermia (MFH) for the treatment of brain tumors
Funded at Magnetic Insight, INC. · NIH-10877810 · Data updated 2026-11-12
This study is testing a new way to treat brain tumors by using tiny magnetic particles that can be heated to help destroy cancer cells, while also keeping an eye on the temperature to protect healthy tissue, and it's designed for people with recurrent glioblastoma.
Quick facts
| Grant type | Sbir 2 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Magnetic Insight, INC. NIH-funded |
| Lab location | 1 site (Alameda, UNITED STATES) |
| Project start | July 1, 2023 |
| Project end | June 30, 2025 |
| Funding year | 2024 |
| Award (this year) | $1,012,220 |
| NIH project number | 5R44CA285064-02 |
| Project ID | NIH-10877810 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are patients diagnosed with recurrent glioblastoma or other brain tumors who are seeking advanced treatment options.
✕Less likely to help
Patients with non-brain tumors or those who are not eligible for localized treatment may not benefit from this research.
What this research studies
This research focuses on developing a new clinical platform that combines Magnetic Particle Imaging (MPI) and Magnetic Fluid Hyperthermia (MFH) to treat brain tumors. The approach involves delivering magnetic nanoparticles directly to the tumor, which are then heated using alternating magnetic fields to kill cancer cells. The system will also monitor temperature in real-time to ensure effective treatment while minimizing damage to surrounding healthy tissue. This innovative technology aims to improve the effectiveness of existing treatments for recurrent glioblastoma.
Why it matters
Potential benefit: If successful, this research could significantly enhance treatment outcomes for patients with brain tumors by providing a more targeted and effective therapy.
How similar studies have gone: While MFH has been used in clinical settings, this specific combination of MPI and MFH for brain tumors represents a novel approach that has not been extensively tested.
Where this research is happening
-
Magnetic Insight, INC.
Alameda, United States Active
Researchers
- Principal investigator: Goodwill, Patrick — Magnetic Insight, INC.
- Study coordinator: Goodwill, Patrick
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.