Creating a new peptide treatment for traumatic brain injury

Development of a novel peptide therapeutic for traumatic brain injury

NIH-funded research Aivocode, LLP · NIH-11269084

This study is testing a new treatment called CAQK to help people with moderate to severe traumatic brain injuries heal better and recover more fully after their injuries.

Quick facts

Grant typeSbir 2 grant
Study typeNIH-funded research
Funding institutionAivocode, LLP NIH-funded
Lab location1 site (Encinitas, UNITED STATES)
Project IDNIH-11269084 on NIH RePORTER

What this research studies

This research focuses on developing a novel peptide therapeutic called CAQK for treating moderate to severe traumatic brain injury (TBI). The approach involves targeting both penetrating and contusion types of brain injuries to limit secondary damage that occurs after the initial trauma. By conducting efficacy studies in animal models, the research aims to demonstrate the peptide's ability to improve healing and functional recovery. The ultimate goal is to prepare for clinical trials that could lead to new treatment options for patients suffering from TBI.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals who have experienced moderate to severe traumatic brain injuries.

Not a fit: Patients with mild traumatic brain injuries or those who have not recently experienced a brain injury may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could provide a new treatment option that significantly improves recovery outcomes for patients with traumatic brain injuries.

How similar studies have performed: While this approach is innovative, similar research has shown promise in targeting secondary injury mechanisms in traumatic brain injury.

Where this research is happening

Encinitas, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Acquired brain injury
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.