Creating a new peptide treatment for traumatic brain injury
Official title: Development of a novel peptide therapeutic for traumatic brain injury
Funded at Aivocode, LLP · NIH-11269084 · Data updated 2026-11-12
This study is testing a new treatment called CAQK to help people with moderate to severe traumatic brain injuries heal better and recover more fully after their injuries.
Quick facts
| Grant type | Sbir 2 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Aivocode, LLP NIH-funded |
| Lab location | 1 site (Encinitas, UNITED STATES) |
| Project start | February 3, 2025 |
| Project end | March 31, 2026 |
| Funding year | 2025 |
| Award (this year) | $87,001 |
| NIH project number | 3R44NS130776-02S1 |
| Project ID | NIH-11269084 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals who have experienced moderate to severe traumatic brain injuries.
✕Less likely to help
Patients with mild traumatic brain injuries or those who have not recently experienced a brain injury may not benefit from this research.
What this research studies
This research focuses on developing a novel peptide therapeutic called CAQK for treating moderate to severe traumatic brain injury (TBI). The approach involves targeting both penetrating and contusion types of brain injuries to limit secondary damage that occurs after the initial trauma. By conducting efficacy studies in animal models, the research aims to demonstrate the peptide's ability to improve healing and functional recovery. The ultimate goal is to prepare for clinical trials that could lead to new treatment options for patients suffering from TBI.
Why it matters
Potential benefit: If successful, this research could provide a new treatment option that significantly improves recovery outcomes for patients with traumatic brain injuries.
How similar studies have gone: While this approach is innovative, similar research has shown promise in targeting secondary injury mechanisms in traumatic brain injury.
Where this research is happening
-
Aivocode, LLP
Encinitas, United States Active
Researchers
- Principal investigator: Mann, Aman — Aivocode, LLP
- Study coordinator: Mann, Aman
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.