Creating a new pain relief medication to reduce reliance on opioids
Development of a Soluble Epoxide Hydrolase Inhibitor to Spare or Replace Opioid Analgesics
This study is testing a new pain relief medication called EC5026 that aims to help people with nerve pain while reducing the need for opioids, making it a safer option for managing pain.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Eicosis, LLC NIH-funded |
| Lab location | 1 site (Davis, UNITED STATES) |
| Project ID | NIH-11001990 on NIH RePORTER |
What this research studies
This research focuses on developing a novel analgesic called EC5026, which aims to effectively manage neuropathic pain while minimizing the need for opioid medications. The approach involves targeting a specific enzyme, soluble epoxide hydrolase, to enhance the body's natural pain relief mechanisms. The research includes preclinical studies and plans for clinical trials to evaluate the safety and effectiveness of EC5026 in humans, with the goal of providing a safer alternative to traditional opioid treatments.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals suffering from chronic neuropathic pain who are currently using or are at risk of using opioids for pain management.
Not a fit: Patients who do not experience chronic pain or those who are not at risk of opioid use disorders may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to a new pain management option that reduces the risk of opioid addiction and improves quality of life for patients with chronic pain.
How similar studies have performed: Other research has shown promise in developing non-opioid analgesics, but this specific approach targeting soluble epoxide hydrolase is relatively novel.
Where this research is happening
Davis, UNITED STATES
- Eicosis, LLC — Davis, United States (Active)
Researchers
- Principal investigator: Cortes-Puch, Irene — Eicosis, LLC
- Study coordinator: Cortes-Puch, Irene
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.