NIH-funded research R21 grant

Creating a new noninvasive test to detect retinal problems early

Official title: Development of a novel, noninvasive, sensitive measure of retinal dysfunction

Funded at University of California, San Francisco · NIH-11064593 · Data updated 2026-11-12

This study is working on a new, easy way to check for early signs of eye problems in people with diabetic retinopathy, so doctors can catch issues before they affect your vision and help prevent vision loss.

Quick facts

Grant typeR21 grant
Study typeNIH-funded research
Funding institutionUniversity of California, San Francisco
NIH-funded
Lab location1 site (San Francisco, United States)
Project startJanuary 1, 2025
Project endDecember 31, 2026
Funding year2025
Award (this year)$245,733
NIH project number1R21EY036209-01A1
Project IDNIH-11064593 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research include individuals at risk for diabetic retinopathy, particularly those with diabetes.

Less likely to help

Patients with retinal conditions unrelated to diabetic retinopathy or those who have already experienced significant vision loss may not benefit from this research.

What this research studies

This research focuses on developing a novel, noninvasive method to measure retinal dysfunction, particularly in conditions like diabetic retinopathy. By utilizing advanced imaging techniques, the study aims to identify early signs of retinal damage before patients experience visual symptoms. This approach could lead to timely interventions that may prevent vision loss. The research seeks to create a more accessible diagnostic tool that can be integrated into routine clinical practice.

Why it matters

Potential benefit: If successful, this research could significantly improve early detection and treatment of retinal diseases, potentially preventing vision loss in millions of patients.

How similar studies have gone: Previous research using advanced imaging techniques like adaptive optics has shown promise in detecting retinal dysfunction, indicating that this approach may build on established methods.

Where this research is happening

  • University of California, San Francisco
    San Francisco, United States
    Active

Researchers

  • Principal investigator: Dunn, Felice a — University of California, San Francisco
  • Study coordinator: Dunn, Felice a

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About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.