Creating a new model using hen's eggs to test for DNA damage from chemicals
Development of a Comprehensive Hen's Egg Model for Genotoxicity Testing
['FUNDING_SBIR_2'] · LITRON LABORATORIES, LTD. · NIH-11006886
This study is creating a new way to test if certain medicines and chemicals can harm DNA, using hen's eggs instead of animals, to help us better understand cancer risks and keep people safe.
Quick facts
| Phase | ['FUNDING_SBIR_2'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | LITRON LABORATORIES, LTD. (nih funded) |
| Locations | 1 site (ROCHESTER, UNITED STATES) |
| Trial ID | NIH-11006886 on ClinicalTrials.gov |
What this research studies
This research aims to develop a hen's egg model that can effectively assess the genotoxicity of various pharmaceuticals and industrial chemicals. By mimicking human physiological responses, this model seeks to evaluate the potential of these substances to damage DNA, which is crucial for understanding cancer risks. The approach focuses on creating a non-animal testing system that retains metabolic activity, allowing for a more accurate representation of how these chemicals may affect human health. This innovative method could replace traditional animal testing, which is increasingly being restricted.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals concerned about the safety of pharmaceuticals and chemicals they may be exposed to.
Not a fit: Patients who are not affected by or do not use pharmaceuticals or industrial chemicals may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to safer chemical assessments and reduce reliance on animal testing in toxicology.
How similar studies have performed: While there have been advancements in non-animal testing methods, this specific approach using hen's eggs is relatively novel and untested.
Where this research is happening
ROCHESTER, UNITED STATES
- LITRON LABORATORIES, LTD. — ROCHESTER, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: BRIGGS, ERICA — LITRON LABORATORIES, LTD.
- Study coordinator: BRIGGS, ERICA
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.