Creating a new model to study heart problems in diabetes
Development and validation of a novel bioprinted, human-diabetic cardiac organoid model
This study is creating a new heart model using special printing technology to help us understand and find better treatments for heart problems caused by type-2 diabetes, so that patients can get care that's more suited to their needs.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Texas El Paso NIH-funded |
| Lab location | 1 site (El Paso, United States) |
| Project ID | NIH-10687914 on NIH RePORTER |
What this research studies
This research focuses on developing a novel cardiac organoid model using bioprinting technology to better understand diabetic cardiomyopathy, a serious heart condition linked to type-2 diabetes. By utilizing human cardiac cells from diabetic donors, the researchers aim to create a more accurate representation of heart tissue that can mimic disease progression and respond to diabetic stress. This model will serve as a platform for screening potential treatments, addressing the limitations of current animal-based studies. Patients may benefit from improved therapeutic strategies that are specifically tailored to their condition.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with type-2 diabetes who are at risk of developing heart problems.
Not a fit: Patients without diabetes or those who do not have cardiovascular complications may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective treatments for heart complications in diabetic patients.
How similar studies have performed: While the approach of using bioprinted human cardiac models is innovative, similar studies have shown promise in other areas of tissue engineering and disease modeling.
Where this research is happening
El Paso, United States
- University of Texas El Paso — El Paso, United States (Active)
Researchers
- Principal investigator: Han, Kyung-an — University of Texas El Paso
- Study coordinator: Han, Kyung-an
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.